Company announces Phase 2 part of the EBO-301 trial is now fully enrolled with 80 patients; Topline Phase 2 trial results expected in summer 2024 Over 100 sites across four countries (U.S., Japan, S. Korea & Australia) as epetraborole enters Phase 3 portion of EBO-301; expected to enroll ~230 patients MENLO PARK, Calif.--(BUSINESS WIRE)--Sep. 13, 2023-- AN2 Therapeutics, Inc. (Nasdaq: ANTX), a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today announced that it has commenced the Phase 3 part of its Phase 2/3 clinical trial evaluating once-daily, oral epetraborole for treatment-refractory MAC lung disease after completing Phase 2 enrollment. The Phase 2/3 clinical trial is expected to support regulatory filings for approval in the U.S. and Japan. AN2
CAMBRIDGE, Mass., Sept. 20, 2022 /PRNewswire/ -- Octagon Therapeutics, a preclinical-stage biopharmaceutical company developing targeted medicines for autoimmune disease, today announced the initiation of a research collaboration with Novo Nordisk focused on inflammatory disease. This multi-year relationship will apply Octagon's functional target discovery approach and novel chemistry strategy in disease areas in which Novo Nordisk has specific expertise. Octagon's lead program selectively targets a population of pathologically activated B cells that contribute to autoimmune diseases like systemic lupus and vasculitis. This same approach can be applied in other disease areas to target disease-driving processes while sparing healthy immune functioning. A pilot project, through the Novo Nordisk Co-creation Greenhouse accelerator program, demonstrated proof-of-concept in identifying atypical characteristics of other immune cells during disease, leading
MENLO PARK, Calif., March 24, 2022 (GLOBE NEWSWIRE) -- AN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing treatments for rare, chronic, and serious infectious diseases with high unmet needs, today announced the pricing of its upsized initial public offering of 4,600,000 shares of its common stock at a price to the public of $15.00 per share. All of the shares of common stock are being offered by AN2 Therapeutics. The gross proceeds to AN2 Therapeutics from the offering, before deducting underwriting discounts and commissions and other offering expenses payable by AN2 Therapeutics, are expected to be $69.0 million. In addition, AN2 Therapeutics has granted the underwriters a 30-day option to purchase up to an additional 690,000 shares of
Financing co-led by seasoned healthcare investors, CAM Capital and Polaris Partners SAN DIEGO--(BUSINESS WIRE)-- Primmune Therapeutics today announced the initial closing of a $27.4 million Series A financing to advance the development of novel orally-administered, small molecule toll-like receptor 7 (TLR7) agonists as therapeutic-adjuvants for acute viral diseases and cancer. The financing was co-led by CAM Capital and Polaris Partners and included new investors Samsara BioCapital and Oberland Capital as well as existing investors McDermott, BioRock Ventures and BioBrit. The Series A financing included the conversion of $7.4 million in convertible seed capital securities. Concurrent with the closing, Amir Nashat, Managing Partner at Polaris Partners and Andrew Rubinstein, Managing Partner at Oberland Capital will join the board of directors. “This financing will enable
FOSTER CITY, Calif., June 16, 2020 (GLOBE NEWSWIRE) -- Vaxcyte, Inc. (Nasdaq: PCVX), a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide, today announced the closing of its initial public offering of 17,968,750 shares of common stock, which includes the full exercise of the underwriters’ option to purchase 2,343,750 additional shares of common stock, at a public offering price of $16.00 per share. All of the shares were offered by Vaxcyte. The aggregate gross proceeds from the offering were $287.5 million, before deducting underwriting discounts and commissions and offering expenses. The shares began trading on the Nasdaq Global Select Market under the ticker symbol “PCVX” on June 12,